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Genetically detoxified tetanus toxin as a vaccine and conjugate carrier protein

Tetanus toxoid (TTxd), developed over 100 years ago, is a clinically effective, legacy vaccine against tetanus. Due to the extreme potency of native tetanus toxin, manufacturing and regulatory efforts often focus on TTxd production, standardization, and safety, rather than product modernization. Rec...

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Detalles Bibliográficos
Autores principales: Chang, Min-Ju, Ollivault-Shiflett, Morgane, Schuman, Richard, Nguyen, Son Ngoc, Kaltashov, Igor A., Bobst, Cedric, Rajagopal, Shalini P., Przedpelski, Amanda, Barbieri, Joseph T., Lees, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336728/
https://www.ncbi.nlm.nih.gov/pubmed/35871872
http://dx.doi.org/10.1016/j.vaccine.2022.07.011

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