Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model

This study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altere...

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Detalles Bibliográficos
Autores principales: Sanada, Takayuki J., Hosomi, Koji, Park, Jonguk, Naito, Akira, Sakao, Seiichiro, Tanabe, Nobuhiro, Kunisawa, Jun, Tatsumi, Koichiro, Suzuki, Takuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336776/
https://www.ncbi.nlm.nih.gov/pubmed/37448440
http://dx.doi.org/10.1002/pul2.12266
Descripción
Sumario:This study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altered gut microbiota composition.

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