Octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: A case series and review of literature

Excessive bronchial secretions pose a challenge in mechanically-ventilated patients and may prolong the time to extubation, increasing the risk for pneumonia. Octreotide, a somatostatin analog, has been used to decrease bronchial secretions especially for the symptomatic management of patients with...

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Detalles Bibliográficos
Autores principales: Bhandari, Sambhawana, Sostin, Oleg, Shah, Akash, Chronakos, John, Kahn, Douglas, Mendez, Jose, Hegde, Abhijith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336782/
https://www.ncbi.nlm.nih.gov/pubmed/37448885
http://dx.doi.org/10.1016/j.rmcr.2023.101891
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author Bhandari, Sambhawana
Sostin, Oleg
Shah, Akash
Chronakos, John
Kahn, Douglas
Mendez, Jose
Hegde, Abhijith
author_facet Bhandari, Sambhawana
Sostin, Oleg
Shah, Akash
Chronakos, John
Kahn, Douglas
Mendez, Jose
Hegde, Abhijith
author_sort Bhandari, Sambhawana
collection PubMed
description Excessive bronchial secretions pose a challenge in mechanically-ventilated patients and may prolong the time to extubation, increasing the risk for pneumonia. Octreotide, a somatostatin analog, has been used to decrease bronchial secretions especially for the symptomatic management of patients with lung cancer. We describe three patients in the form of a case series and discuss effect of octretotide on bronchial secretions and management of bronchorrhea in the intensive care unit. Similar to reports of its utilization in palliative care in patients with lung cancer, we observed a clinically significant decrease in the rate of bronchial secretions.
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spelling pubmed-103367822023-07-13 Octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: A case series and review of literature Bhandari, Sambhawana Sostin, Oleg Shah, Akash Chronakos, John Kahn, Douglas Mendez, Jose Hegde, Abhijith Respir Med Case Rep Case Report Excessive bronchial secretions pose a challenge in mechanically-ventilated patients and may prolong the time to extubation, increasing the risk for pneumonia. Octreotide, a somatostatin analog, has been used to decrease bronchial secretions especially for the symptomatic management of patients with lung cancer. We describe three patients in the form of a case series and discuss effect of octretotide on bronchial secretions and management of bronchorrhea in the intensive care unit. Similar to reports of its utilization in palliative care in patients with lung cancer, we observed a clinically significant decrease in the rate of bronchial secretions. Elsevier 2023-07-04 /pmc/articles/PMC10336782/ /pubmed/37448885 http://dx.doi.org/10.1016/j.rmcr.2023.101891 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bhandari, Sambhawana
Sostin, Oleg
Shah, Akash
Chronakos, John
Kahn, Douglas
Mendez, Jose
Hegde, Abhijith
Octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: A case series and review of literature
title Octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: A case series and review of literature
title_full Octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: A case series and review of literature
title_fullStr Octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: A case series and review of literature
title_full_unstemmed Octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: A case series and review of literature
title_short Octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: A case series and review of literature
title_sort octreotide as a novel agent for the management of bronchorrhea in mechanically ventilated patients: a case series and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336782/
https://www.ncbi.nlm.nih.gov/pubmed/37448885
http://dx.doi.org/10.1016/j.rmcr.2023.101891
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