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Interferon-γ regulates immunosuppression in septic mice by promoting the Warburg effect through the PI3K/AKT/mTOR pathway

BACKGROUND: The main cause of high mortality from sepsis is that immunosuppression leads to life-threatening organ dysfunction, and reversing immunosuppression is key to sepsis treatment. Interferon γ (IFNγ) is a potential therapy for immunosuppression of sepsis, promoting glycolysis to restore meta...

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Detalles Bibliográficos
Autores principales:	Fu, Xu-zhe, Wang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337057/ https://www.ncbi.nlm.nih.gov/pubmed/37434129 http://dx.doi.org/10.1186/s10020-023-00690-x

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