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PHF5A regulates the expression of the DOCK5 variant to promote HNSCC progression through p38 MAPK activation

BACKGROUND: Previously, we identified an oncogenic splicing variant of DOCK5 in head and neck squamous cell carcinoma (HNSCC); however, the mechanism for the generation of this specific DOCK5 variant remains unknown. This study aims to explore the potential spliceosome genes involved in the producti...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Li, Guo, Zheng, Siyuan, She, Li, Lu, Shanhong, Wang, Yunyun, Huang, Donghai, Zhang, Xin, Sun, Lunquan, Liu, Yong, Qiu, Yuanzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337101/
https://www.ncbi.nlm.nih.gov/pubmed/37434235
http://dx.doi.org/10.1186/s13062-023-00396-4

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