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Expression and role of the immune checkpoint regulator PD-L1 in the tumor-stroma interplay of pancreatic ductal adenocarcinoma

INTRODUCTION: Immune checkpoint inhibitors (ICI), e.g., targeting programmed cell death protein 1-ligand 1 (PD-L1) or its receptor PD-1, have markedly improved the therapy of many cancers but so far failed in pancreatic ductal adenocarcinoma (PDAC). Macrophages represent one of the most abundant imm...

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Detalles Bibliográficos
Autores principales:	Daunke, Tina, Beckinger, Silje, Rahn, Sascha, Krüger, Sandra, Heckl, Steffen, Schäfer, Heiner, Wesch, Daniela, Pilarsky, Christian, Eckstein, Markus, Hartmann, Arndt, Röcken, Christoph, Wandmacher, Anna Maxi, Sebens, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337136/ https://www.ncbi.nlm.nih.gov/pubmed/37449210 http://dx.doi.org/10.3389/fimmu.2023.1157397

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