Host obesity alters the ovarian tumor immune microenvironment and impacts response to standard of care chemotherapy

BACKGROUND: The majority of women with epithelial ovarian cancer (OvCa) are diagnosed with metastatic disease, resulting in a poor 5-year survival of 31%. Obesity is a recognized non-infectious pandemic that increases OvCa incidence, enhances metastatic success and reduces survival. We have previous...

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Detalles Bibliográficos
Autores principales: Liu, Yueying, Yang, Jing, Hilliard, Tyvette S., Wang, Zhikun, Johnson, Jeff, Wang, Wanrui, Harper, Elizabeth I., Ott, Connor, O’Brien, Caitlin, Campbell, Leigh, Crowley, Brian, Grisoli, Stephen, Stavrou, Nicholas M., Juncker-Jensen, Anna, Stack, M. Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337170/
https://www.ncbi.nlm.nih.gov/pubmed/37438818
http://dx.doi.org/10.1186/s13046-023-02740-y

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