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Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract

PURPOSE: To observe the distribution characteristics of corneal higher-order aberrations (HOAs) in cataract patients, and analyze the relationship of HOAs with patients’ age and ocular biometric parameters. METHODS: This retrospective study reviews the patients with cataract in Wuhan Aier Eye Depart...

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Autores principales: Zhou, Suowang, Chen, Xu, Ortega-Usobiaga, Julio, Zheng, Hansong, Luo, Wenjing, Tu, Biyue, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337181/
https://www.ncbi.nlm.nih.gov/pubmed/37438729
http://dx.doi.org/10.1186/s12886-023-03067-0
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author Zhou, Suowang
Chen, Xu
Ortega-Usobiaga, Julio
Zheng, Hansong
Luo, Wenjing
Tu, Biyue
Wang, Yong
author_facet Zhou, Suowang
Chen, Xu
Ortega-Usobiaga, Julio
Zheng, Hansong
Luo, Wenjing
Tu, Biyue
Wang, Yong
author_sort Zhou, Suowang
collection PubMed
description PURPOSE: To observe the distribution characteristics of corneal higher-order aberrations (HOAs) in cataract patients, and analyze the relationship of HOAs with patients’ age and ocular biometric parameters. METHODS: This retrospective study reviews the patients with cataract in Wuhan Aier Eye Department from January to August 2022. Root mean square (RMS) of the total HOA (tHOA), spherical aberration (SA), coma and trefoil aberration of the anterior cornea at central 4 and 6 mm optic zone were measured by the Wavefront Aberrometer (OPD-Scan III; Nidek Inc, Tokyo, Japan). The biometric parameters including axial length (AL), keratometry (K), central corneal thickness (CCT) and lens thickness (LT) were measured by swept-source coherence laser interferometry (OA-2000; TOMEY Corp, Aichi, Japan). Subgroup analyses and multiple linear regression analyses were used to determine whether HOAs were associated with age and ocular biometric parameters. RESULTS: A total of 976 patients (976 eyes) were included, averagely aged 65 years. At central 4 and 6 mm optic zone, the mean RMS of tHOA were respectively 0.20 and 0.65 μm, the SA were 0.06 and 0.30 μm, the coma aberration were 0.11 and 0.35 μm, and the trefoil aberration were 0.12 and 0.30 μm. The tHOA decreased with age until 60 years and then started to increase afterwards. The tHOA, coma and trefoil aberration increased with corneal astigmatism. The tHOA, SA, and coma aberration differ among different AL groups, and emmetropes had the smallest tHOA, SA, and coma aberration. CONCLUSIONS: With increasing age, the value of tHOA decrease first and started increasing at 60 years. The trends of corneal HOAs are consistent with corneal low-order aberrations. The values of tHOA, SA and coma aberration were the smallest in emmetropic eyes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12886-023-03067-0.
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spelling pubmed-103371812023-07-13 Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract Zhou, Suowang Chen, Xu Ortega-Usobiaga, Julio Zheng, Hansong Luo, Wenjing Tu, Biyue Wang, Yong BMC Ophthalmol Research PURPOSE: To observe the distribution characteristics of corneal higher-order aberrations (HOAs) in cataract patients, and analyze the relationship of HOAs with patients’ age and ocular biometric parameters. METHODS: This retrospective study reviews the patients with cataract in Wuhan Aier Eye Department from January to August 2022. Root mean square (RMS) of the total HOA (tHOA), spherical aberration (SA), coma and trefoil aberration of the anterior cornea at central 4 and 6 mm optic zone were measured by the Wavefront Aberrometer (OPD-Scan III; Nidek Inc, Tokyo, Japan). The biometric parameters including axial length (AL), keratometry (K), central corneal thickness (CCT) and lens thickness (LT) were measured by swept-source coherence laser interferometry (OA-2000; TOMEY Corp, Aichi, Japan). Subgroup analyses and multiple linear regression analyses were used to determine whether HOAs were associated with age and ocular biometric parameters. RESULTS: A total of 976 patients (976 eyes) were included, averagely aged 65 years. At central 4 and 6 mm optic zone, the mean RMS of tHOA were respectively 0.20 and 0.65 μm, the SA were 0.06 and 0.30 μm, the coma aberration were 0.11 and 0.35 μm, and the trefoil aberration were 0.12 and 0.30 μm. The tHOA decreased with age until 60 years and then started to increase afterwards. The tHOA, coma and trefoil aberration increased with corneal astigmatism. The tHOA, SA, and coma aberration differ among different AL groups, and emmetropes had the smallest tHOA, SA, and coma aberration. CONCLUSIONS: With increasing age, the value of tHOA decrease first and started increasing at 60 years. The trends of corneal HOAs are consistent with corneal low-order aberrations. The values of tHOA, SA and coma aberration were the smallest in emmetropic eyes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12886-023-03067-0. BioMed Central 2023-07-12 /pmc/articles/PMC10337181/ /pubmed/37438729 http://dx.doi.org/10.1186/s12886-023-03067-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zhou, Suowang
Chen, Xu
Ortega-Usobiaga, Julio
Zheng, Hansong
Luo, Wenjing
Tu, Biyue
Wang, Yong
Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract
title Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract
title_full Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract
title_fullStr Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract
title_full_unstemmed Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract
title_short Characteristics and influencing factors of corneal higher-order aberrations in patients with cataract
title_sort characteristics and influencing factors of corneal higher-order aberrations in patients with cataract
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337181/
https://www.ncbi.nlm.nih.gov/pubmed/37438729
http://dx.doi.org/10.1186/s12886-023-03067-0
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