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EXPLORING THE INTERPLAY BETWEEN BRAIN TUMOUR INITIATING CELLS AND THE TUMOUR MICROENVIRONMENT: POTENTIAL TARGETING STRATEGIES FOR GLIOBLASTOMA
The aggressive biology and poor response to therapy resulting in relapse of patients with GBM is attributed to the existence of Brain Tumour Initiating Cells (BTICs) with stem cell properties. Targeting BTICs in isolation of their surrounding tumour microenvironment (TME) has proven ineffective. Det...
Autores principales: | Lubanska, Dorota, Alrashed, Sami, Sorge, Alexandra, Cieslukowski, Alan, Mahendran, Hema Priya, Nadeem, Fatima, Shamisa, Abdalla, deCarvalho, Ana, Kulkarni, Swati, Soliman, Mohamed A R, Rondeau-Gagne, Simon, Porter, Lisa A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337549/ http://dx.doi.org/10.1093/noajnl/vdad071.021 |
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