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HIGH-DIMENSIONAL HISTOPATHOLOGIC EVALUATION OF THE HYPOXIC MICROENVIRONMENT IN GLIOBLASTOMA
Rapidly growing solid tumors such as glioblastoma (GBM) are characteristically hypoxic, displaying large areas of necrosis surrounded by hyperproliferative pseudopalisading cells. Intra-tumoral hypoxia develops over time in the three-dimensional space and the degree of tissue oxygenation is a dynami...
Autores principales: | Mansouri, Sheila, Zaidi, Mark, Singh, Olivia, Karimi, Shirin, Lombard, Phoebe, Dvorkin-Gheva, Anna, Velasquez, Carlos, Ali, Hafsah, Devaraja, Kaviya, Sosa, Julio, Patil, Vikas, Wei, QingXia, Wu, Ronald, Li, Mira, Cheung, May, Voisin, Mathew, Gao, Andrew, Hedley, David, Aldape, Kenneth, Wouters, Bradly, Zadeh, Gelareh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337557/ http://dx.doi.org/10.1093/noajnl/vdad071.023 |
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