Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report

Sarcoidosis is a multi-organ medical condition that is characterized by the formation of granulomas. We aimed to identify a correlation between each sarcoidosis blood biomarker and cystatin C (Cys-C) in sarcoidosis patients. We report a case of a 60-year-old man with sarcoidosis. The correlation bet...

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Autores principales: Fukunaga, Shohei, Itoga, Kenichi, Sonoda, Hirotaka, Hoshino, Yuki, Yoshimura, Ryuichi, Egawa, Masahiro, Ito, Takafumi, Tanabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Allergy/Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337699/
https://www.ncbi.nlm.nih.gov/pubmed/37448407
http://dx.doi.org/10.7759/cureus.40304
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author Fukunaga, Shohei
Itoga, Kenichi
Sonoda, Hirotaka
Hoshino, Yuki
Yoshimura, Ryuichi
Egawa, Masahiro
Ito, Takafumi
Tanabe, Kazuaki
author_facet Fukunaga, Shohei
Itoga, Kenichi
Sonoda, Hirotaka
Hoshino, Yuki
Yoshimura, Ryuichi
Egawa, Masahiro
Ito, Takafumi
Tanabe, Kazuaki
author_sort Fukunaga, Shohei
collection PubMed
description Sarcoidosis is a multi-organ medical condition that is characterized by the formation of granulomas. We aimed to identify a correlation between each sarcoidosis blood biomarker and cystatin C (Cys-C) in sarcoidosis patients. We report a case of a 60-year-old man with sarcoidosis. The correlation between his Cys-C and each blood biomarker level and that between each blood biomarker and serum creatinine levels were determined using linear regression. Serum Cys-C correlated with each blood biomarker of sarcoidosis, while creatinine did not. These findings suggest that Cys-C is a potential blood biomarker for sarcoidosis.
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spelling pubmed-103376992023-07-13 Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report Fukunaga, Shohei Itoga, Kenichi Sonoda, Hirotaka Hoshino, Yuki Yoshimura, Ryuichi Egawa, Masahiro Ito, Takafumi Tanabe, Kazuaki Cureus Allergy/Immunology Sarcoidosis is a multi-organ medical condition that is characterized by the formation of granulomas. We aimed to identify a correlation between each sarcoidosis blood biomarker and cystatin C (Cys-C) in sarcoidosis patients. We report a case of a 60-year-old man with sarcoidosis. The correlation between his Cys-C and each blood biomarker level and that between each blood biomarker and serum creatinine levels were determined using linear regression. Serum Cys-C correlated with each blood biomarker of sarcoidosis, while creatinine did not. These findings suggest that Cys-C is a potential blood biomarker for sarcoidosis. Cureus 2023-06-12 /pmc/articles/PMC10337699/ /pubmed/37448407 http://dx.doi.org/10.7759/cureus.40304 Text en Copyright © 2023, Fukunaga et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Allergy/Immunology
Fukunaga, Shohei
Itoga, Kenichi
Sonoda, Hirotaka
Hoshino, Yuki
Yoshimura, Ryuichi
Egawa, Masahiro
Ito, Takafumi
Tanabe, Kazuaki
Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report
title Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report
title_full Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report
title_fullStr Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report
title_full_unstemmed Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report
title_short Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report
title_sort cystatin c as a potential blood biomarker for sarcoidosis: a case report
topic Allergy/Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337699/
https://www.ncbi.nlm.nih.gov/pubmed/37448407
http://dx.doi.org/10.7759/cureus.40304
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