Cargando…

Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study

OBJECTIVES: We aimed to prospectively compare lower urinary tract symptoms in premenopausal and postmenopausal women with acute uncomplicated cystitis before and after antibiotic therapy. MATERIALS AND METHODS: This study included adult women with acute uncomplicated cystitis who visited 4 instituti...

Descripción completa

Detalles Bibliográficos
Autores principales: Wanifuchi, Atsushi, Kyoda, Yuki, Ogasawara, Takuto, Kobayashi, Ko, Ito, Naoki, Shindo, Tetsuya, Takahashi, Atsushi, Kunishima, Yasuharu, Masumori, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337814/
https://www.ncbi.nlm.nih.gov/pubmed/37448620
http://dx.doi.org/10.1097/CU9.0000000000000197
_version_ 1785071496324972544
author Wanifuchi, Atsushi
Kyoda, Yuki
Ogasawara, Takuto
Kobayashi, Ko
Ito, Naoki
Shindo, Tetsuya
Takahashi, Atsushi
Kunishima, Yasuharu
Masumori, Naoya
author_facet Wanifuchi, Atsushi
Kyoda, Yuki
Ogasawara, Takuto
Kobayashi, Ko
Ito, Naoki
Shindo, Tetsuya
Takahashi, Atsushi
Kunishima, Yasuharu
Masumori, Naoya
author_sort Wanifuchi, Atsushi
collection PubMed
description OBJECTIVES: We aimed to prospectively compare lower urinary tract symptoms in premenopausal and postmenopausal women with acute uncomplicated cystitis before and after antibiotic therapy. MATERIALS AND METHODS: This study included adult women with acute uncomplicated cystitis who visited 4 institutions between 2019 and 2020. After registration, we administered oral antibiotics and prospectively documented the changes in lower urinary tract symptoms from the first visit to a follow-up visit at 1 week using the Core Lower Urinary Tract Symptoms Score (CLSS) questionnaire. RESULTS: After treatment, pyuria disappeared in 60 of the 66 patients (14 premenopausal and 46 postmenopausal). The CLSS total score (range) changed from 13 (3–29) to 4 (0–18) with a significant improvement in all CLSS items. At baseline, nocturia, urgency, and urgency incontinence were more prominent in postmenopausal women than in premenopausal women. In contrast, baseline urethral pain and quality of life index were more severe in premenopausal women than in postmenopausal women. After treatment, the CLSS total score was still higher in postmenopausal women, as reflected by the relatively higher scores for nocturia and urgency, irrespective of the comparable scores for urethral pain and the quality of life index in the 2 groups. CONCLUSIONS: Our results suggest that if storage symptoms persist, they should be carefully interpreted according to menopausal status.
format Online
Article
Text
id pubmed-10337814
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-103378142023-09-01 Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study Wanifuchi, Atsushi Kyoda, Yuki Ogasawara, Takuto Kobayashi, Ko Ito, Naoki Shindo, Tetsuya Takahashi, Atsushi Kunishima, Yasuharu Masumori, Naoya Curr Urol Special Topic - Advances in Female Urology OBJECTIVES: We aimed to prospectively compare lower urinary tract symptoms in premenopausal and postmenopausal women with acute uncomplicated cystitis before and after antibiotic therapy. MATERIALS AND METHODS: This study included adult women with acute uncomplicated cystitis who visited 4 institutions between 2019 and 2020. After registration, we administered oral antibiotics and prospectively documented the changes in lower urinary tract symptoms from the first visit to a follow-up visit at 1 week using the Core Lower Urinary Tract Symptoms Score (CLSS) questionnaire. RESULTS: After treatment, pyuria disappeared in 60 of the 66 patients (14 premenopausal and 46 postmenopausal). The CLSS total score (range) changed from 13 (3–29) to 4 (0–18) with a significant improvement in all CLSS items. At baseline, nocturia, urgency, and urgency incontinence were more prominent in postmenopausal women than in premenopausal women. In contrast, baseline urethral pain and quality of life index were more severe in premenopausal women than in postmenopausal women. After treatment, the CLSS total score was still higher in postmenopausal women, as reflected by the relatively higher scores for nocturia and urgency, irrespective of the comparable scores for urethral pain and the quality of life index in the 2 groups. CONCLUSIONS: Our results suggest that if storage symptoms persist, they should be carefully interpreted according to menopausal status. Lippincott Williams & Wilkins 2023-09 2023-04-01 /pmc/articles/PMC10337814/ /pubmed/37448620 http://dx.doi.org/10.1097/CU9.0000000000000197 Text en Copyright © 2023 The Authors. Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Special Topic - Advances in Female Urology
Wanifuchi, Atsushi
Kyoda, Yuki
Ogasawara, Takuto
Kobayashi, Ko
Ito, Naoki
Shindo, Tetsuya
Takahashi, Atsushi
Kunishima, Yasuharu
Masumori, Naoya
Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study
title Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study
title_full Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study
title_fullStr Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study
title_full_unstemmed Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study
title_short Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study
title_sort difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: a multi-institutional pilot study
topic Special Topic - Advances in Female Urology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337814/
https://www.ncbi.nlm.nih.gov/pubmed/37448620
http://dx.doi.org/10.1097/CU9.0000000000000197
work_keys_str_mv AT wanifuchiatsushi differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy
AT kyodayuki differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy
AT ogasawaratakuto differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy
AT kobayashiko differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy
AT itonaoki differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy
AT shindotetsuya differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy
AT takahashiatsushi differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy
AT kunishimayasuharu differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy
AT masumorinaoya differenceinsymptommanifestationbetweenpostmenopausalandpremenopausalwomeninacuteuncomplicatedcystitisamultiinstitutionalpilotstudy