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Urgent Revascularization of the Left Proximal Circumflex Following Cessation of Cangrelor Within Six Hours of Procedure

Patients undergoing procedures are often transitioned off anticoagulants using anti-platelet agents with short half-lives as a "bridge." We present the case of a patient with a history of in-stent thromboses who experienced a thrombotic event following a literature-guided bridging protocol...

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Autores principales: Huang, Sherri, Rodriguez, Camilo, Shakfeh, Khalid, Smith, Jorden, Reddy, Koushik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337834/
https://www.ncbi.nlm.nih.gov/pubmed/37448385
http://dx.doi.org/10.7759/cureus.40314
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author Huang, Sherri
Rodriguez, Camilo
Shakfeh, Khalid
Smith, Jorden
Reddy, Koushik
author_facet Huang, Sherri
Rodriguez, Camilo
Shakfeh, Khalid
Smith, Jorden
Reddy, Koushik
author_sort Huang, Sherri
collection PubMed
description Patients undergoing procedures are often transitioned off anticoagulants using anti-platelet agents with short half-lives as a "bridge." We present the case of a patient with a history of in-stent thromboses who experienced a thrombotic event following a literature-guided bridging protocol. This case is one of the first to show that stopping cangrelor within six hours led to a need for urgent revascularization and suggests that the timing for discontinuing bridging agents should be customized based on the patient's history of increased blood clotting.
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spelling pubmed-103378342023-07-13 Urgent Revascularization of the Left Proximal Circumflex Following Cessation of Cangrelor Within Six Hours of Procedure Huang, Sherri Rodriguez, Camilo Shakfeh, Khalid Smith, Jorden Reddy, Koushik Cureus Cardiac/Thoracic/Vascular Surgery Patients undergoing procedures are often transitioned off anticoagulants using anti-platelet agents with short half-lives as a "bridge." We present the case of a patient with a history of in-stent thromboses who experienced a thrombotic event following a literature-guided bridging protocol. This case is one of the first to show that stopping cangrelor within six hours led to a need for urgent revascularization and suggests that the timing for discontinuing bridging agents should be customized based on the patient's history of increased blood clotting. Cureus 2023-06-12 /pmc/articles/PMC10337834/ /pubmed/37448385 http://dx.doi.org/10.7759/cureus.40314 Text en Copyright © 2023, Huang et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Huang, Sherri
Rodriguez, Camilo
Shakfeh, Khalid
Smith, Jorden
Reddy, Koushik
Urgent Revascularization of the Left Proximal Circumflex Following Cessation of Cangrelor Within Six Hours of Procedure
title Urgent Revascularization of the Left Proximal Circumflex Following Cessation of Cangrelor Within Six Hours of Procedure
title_full Urgent Revascularization of the Left Proximal Circumflex Following Cessation of Cangrelor Within Six Hours of Procedure
title_fullStr Urgent Revascularization of the Left Proximal Circumflex Following Cessation of Cangrelor Within Six Hours of Procedure
title_full_unstemmed Urgent Revascularization of the Left Proximal Circumflex Following Cessation of Cangrelor Within Six Hours of Procedure
title_short Urgent Revascularization of the Left Proximal Circumflex Following Cessation of Cangrelor Within Six Hours of Procedure
title_sort urgent revascularization of the left proximal circumflex following cessation of cangrelor within six hours of procedure
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337834/
https://www.ncbi.nlm.nih.gov/pubmed/37448385
http://dx.doi.org/10.7759/cureus.40314
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