A History of Repeated Alcohol Intoxication Promotes Cognitive Impairment and Gene Expression Signatures of Disease Progression in the 3xTg Mouse Model of Alzheimer’s Disease

The impact of alcohol abuse on Alzheimer’s disease (AD) is poorly understood. Here, we show that the onset of neurocognitive impairment in a mouse model of AD is hastened by repeated alcohol intoxication through exposure to alcohol vapor, and we provide a comprehensive gene expression dataset of the...

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Detalles Bibliográficos
Autores principales: Sanna, Pietro Paolo, Cabrelle, Chiara, Kawamura, Tomoya, Mercatelli, Daniele, O'Connor, Nathan, Roberts, Amanda J., Repunte-Canonigo, Vez, Giorgi, Federico M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: Methods/New Tools
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337838/
https://www.ncbi.nlm.nih.gov/pubmed/37308288
http://dx.doi.org/10.1523/ENEURO.0456-22.2023

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