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Interfering with the ERC1–LL5β interaction disrupts plasma membrane–Associated platforms and affects tumor cell motility
Cell migration requires a complex array of molecular events to promote protrusion at the front of motile cells. The scaffold protein LL5β interacts with the scaffold ERC1, and recruits it at plasma membrane–associated platforms that form at the front of migrating tumor cells. LL5 and ERC1 proteins s...
Autores principales: | Ribolla, Lucrezia Maria, Sala, Kristyna, Tonoli, Diletta, Ramella, Martina, Bracaglia, Lorenzo, Bonomo, Isabelle, Gonnelli, Leonardo, Lamarca, Andrea, Brindisi, Matteo, Pierattelli, Roberta, Provenzani, Alessandro, de Curtis, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337942/ https://www.ncbi.nlm.nih.gov/pubmed/37437062 http://dx.doi.org/10.1371/journal.pone.0287670 |
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