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Reconstitution of morphogen shuttling circuits

Developing tissues form spatial patterns by establishing concentration gradients of diffusible signaling proteins called morphogens. The bone morphogenetic protein (BMP) morphogen pathway uses a family of extracellular modulators to reshape signaling gradients by actively “shuttling” ligands to diff...

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Detalles Bibliográficos
Autores principales:	Zhu, Ronghui, Santat, Leah A., Markson, Joseph S., Nandagopal, Nagarajan, Gregrowicz, Jan, Elowitz, Michael B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337948/ https://www.ncbi.nlm.nih.gov/pubmed/37436981 http://dx.doi.org/10.1126/sciadv.adf9336

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