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Therapeutic strategies to overcome EGFR mutations as acquired resistance mechanism in ALK-rearranged non-small-cell lung cancer: Case Reports

INTRODUCTION: ALK tyrosine kinase inhibitors (ALK TKIs) have improved prognosis in ALK-rearranged (ALK (+)) non-small-cell lung cancer (NSCLC). However, drug resistance mechanisms occur inevitably during the course of treatment leading to disease progression. Activation of epidermal growth factor re...

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Detalles Bibliográficos
Autores principales:	Michaux, Lionel, Perrier, Alexandre, Mehlman, Camille, Alshehhi, Hussa, Dubois, Antonin, Lacave, Roger, Coulet, Florence, Cadranel, Jacques, Fallet, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338053/ https://www.ncbi.nlm.nih.gov/pubmed/37448514 http://dx.doi.org/10.3389/fonc.2023.1182558

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