Macrophage IL-1β contributes to tumorigenesis through paracrine AIM2 inflammasome activation in the tumor microenvironment

Intracellular recognition of self and non-self -nucleic acids can result in the initiation of effective pro-inflammatory and anti-tumorigenic responses. We hypothesized that macrophages can be activated by tumor-derived nucleic acids to induce inflammasome activation in the tumor microenvironment. W...

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Detalles Bibliográficos
Autores principales: Chew, Zhi Huan, Cui, Jianzhou, Sachaphibulkij, Karishma, Tan, Isabelle, Kar, Shreya, Koh, Kai Kiat, Singh, Kritika, Lim, Hong Meng, Lee, Soo Chin, Kumar, Alan Prem, Gasser, Stephan, Lim, Lina H. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338081/
https://www.ncbi.nlm.nih.gov/pubmed/37449203
http://dx.doi.org/10.3389/fimmu.2023.1211730

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