Seizures regulate the cation-Cl(−) cotransporter NKCC1 in a hamster model of epilepsy: implications for GABA neurotransmission

BACKGROUND: The balance between the activity of the Na(+)/K(+)/Cl(−) cotransporter (NKCC1) that introduces Cl(−) into the cell and the K(+)/Cl(−) cotransporter (KCC2) that transports Cl(−) outside the cell is critical in determining the inhibitory or excitatory outcome of GABA release. Mounting evid...

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Detalles Bibliográficos
Autores principales: Bonet-Fernández, Juan-Manuel, Tranque, Pedro, Aroca-Aguilar, Jose Daniel, Muñoz, Luis J., López, Dolores E., Escribano, Julio, de Cabo, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338185/
https://www.ncbi.nlm.nih.gov/pubmed/37448751
http://dx.doi.org/10.3389/fneur.2023.1207616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338185/
https://www.ncbi.nlm.nih.gov/pubmed/37448751
http://dx.doi.org/10.3389/fneur.2023.1207616

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