Targeting lysyl-oxidase (LOX) may facilitate intramural periarterial drainage for the treatment of Alzheimer's disease

Alzheimer's disease is the commonest form of dementia. It is likely that a lack of clearance of amyloid beta (Aβ) results in its accumulation in the parenchyma as Aβ oligomers and insoluble plaques, and within the walls of blood vessels as cerebral amyloid angiopathy (CAA). The drainage of Aβ a...

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Detalles Bibliográficos
Autores principales: Kelly, Louise, Sharp, Matthew Macgregor, Thomas, Isabelle, Brown, Christopher, Schrag, Matthew, Antunes, Lissa Ventura, Solopova, Elena, Martinez-Gonzalez, José, Rodríguez, Cristina, Carare, Roxana Octavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338210/
https://www.ncbi.nlm.nih.gov/pubmed/37457664
http://dx.doi.org/10.1016/j.cccb.2023.100171

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