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Selective activation of PPARα maintains thermogenic capacity of beige adipocytes
Beige adipocytes are inducible thermogenic adipocytes used for anti-obesity treatment. Beige adipocytes rapidly lose their thermogenic capacity once external cues are removed. However, long-term administration of stimulants, such as PPARγ and β-adrenergic receptor agonists, is unsuitable due to vari...
Autores principales: | Egusa, Gentaro, Ohno, Haruya, Nagano, Gaku, Sagawa, Junji, Shinjo, Hiroko, Yamamoto, Yutaro, Himeno, Natsumi, Morita, Yoshimi, Kanai, Akinori, Baba, Ryuta, Kobuke, Kazuhiro, Oki, Kenji, Yoneda, Masayasu, Hattori, Noboru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338232/ https://www.ncbi.nlm.nih.gov/pubmed/37456852 http://dx.doi.org/10.1016/j.isci.2023.107143 |
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