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Functional and structural characterization of Streptococcus pneumoniae pyruvate kinase involved in fosfomycin resistance
Glycolysis is the primary metabolic pathway in the strictly fermentative Streptococcus pneumoniae, which is a major human pathogen associated with antibiotic resistance. Pyruvate kinase (PYK) is the last enzyme in this pathway that catalyzes the production of pyruvate from phosphoenolpyruvate (PEP)...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338316/ https://www.ncbi.nlm.nih.gov/pubmed/37286036 http://dx.doi.org/10.1016/j.jbc.2023.104892 |