Cargando…

An open-label, acute clinical trial in adults to assess ketone levels, gastrointestinal tolerability, and sleepiness following consumption of (R)-1,3-butanediol (Avela™)

Introduction: A study was undertaken to determine the acute effects of a beverage made with Avela™ (R)-1,3-butanediol, on blood beta-hydroxybutyrate (BHB) levels (using the Keto-Mojo monitor), gastrointestinal (GI) tolerability (using the modified visual analogue scale GI Symptoms Tool), and sleepin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lowder, James, Fallah, Shafagh, Venditti, Carolina, Musa-Veloso, Kathy, Kotlov, Vassili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338333/ https://www.ncbi.nlm.nih.gov/pubmed/37457035 http://dx.doi.org/10.3389/fphys.2023.1195702

Ejemplares similares

Assessment of Intakes and Patterns of Cooked Oatmeal Consumption in the U.S. Using Data from the National Health and Nutrition Examination Surveys
por: Musa-Veloso, Kathy, et al.
Publicado: (2016)

Dietary Inclusion of 1,3-Butanediol Increases Dam Circulating Ketones and Increases Progeny Birth Weight
por: Wijesiriwardana, Udani, et al.
Publicado: (2019)

Synthesis of α-hydroxy ketones and vicinal (R,R)-diols by Bacillus clausii DSM 8716(T) butanediol dehydrogenase
por: Muschallik, Lukas, et al.
Publicado: (2020)

Contribution of 100% Fruit Juice to Micronutrient Intakes in the United States, United Kingdom and Brazil
por: Mitchell, Ellen S., et al.
Publicado: (2020)

Ketone Ester D‐β‐Hydroxybutyrate‐(R)‐1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice
por: Thai, Phung N., et al.
Publicado: (2021)

Mechanism of microbial production of acetoin and 2,3-butanediol optical isomers and substrate specificity of butanediol dehydrogenase
por: Li, Yuchen, et al.
Publicado: (2023)

A randomized, open-label, parallel pilot study investigating metabolic product kinetics of the novel ketone ester, bis-hexanoyl (R)-1,3-butanediol, over one week of ingestion in healthy adults
por: Mah, Eunice, et al.
Publicado: (2023)

Gastrointestinal Effects and Tolerance of Nondigestible Carbohydrate Consumption
por: Mysonhimer, Annemarie R, et al.
Publicado: (2022)

Improved Production of 2,3-Butanediol in Bacillus amyloliquefaciens by Over-Expression of Glyceraldehyde-3-Phosphate Dehydrogenase and 2,3-butanediol Dehydrogenase
por: Yang, Taowei, et al.
Publicado: (2013)

Deletion of meso-2,3-butanediol dehydrogenase gene budC for enhanced D-2,3-butanediol production in Bacillus licheniformis
por: Qi, Gaofu, et al.
Publicado: (2014)

Engineering Corynebacterium glutamicum for the production of 2,3-butanediol
por: Radoš, Dušica, et al.
Publicado: (2015)

Efficient (3S)-Acetoin and (2S,3S)-2,3-Butanediol Production from meso-2,3-Butanediol Using Whole-Cell Biocatalysis
por: He, Yuanzhi, et al.
Publicado: (2018)

Starvation Ketoacidosis Induced by Ketogenic Diet and Consumption of Ketone Supplement
por: Malhi, Manjot S, et al.
Publicado: (2021)

Engineering Bacillus licheniformis for the production of meso-2,3-butanediol
por: Qiu, Yimin, et al.
Publicado: (2016)

Sleepy Genes
por: O'Hara, Bruce F., et al.
Publicado: (2010)

Improved xylose tolerance and 2,3-butanediol production of Klebsiella pneumoniae by directed evolution of rpoD and the mechanisms revealed by transcriptomics
por: Guo, Xue-Wu, et al.
Publicado: (2018)

Exogenous Bio-Based 2,3-Butanediols Enhanced Abiotic Stress Tolerance of Tomato and Turfgrass under Drought or Chilling Stress
por: Park, Ae Ran, et al.
Publicado: (2022)

Improved 2,3-Butanediol Production Rate of Metabolically Engineered Saccharomyces cerevisiae by Deletion of RIM15 and Activation of Pyruvate Consumption Pathway
por: Sugimura, Masahiko, et al.
Publicado: (2023)

The effects of almond consumption on fasting blood lipid levels: a systematic review and meta-analysis of randomised controlled trials
por: Musa-Veloso, Kathy, et al.
Publicado: (2016)

Selegiline improves excessive daytime sleepiness in Parkinson's disease: an open-label observational study
por: Zhang, Jinru, et al.
Publicado: (2022)

Nintendo Wii Fit-Based Sleepiness Testing is Not Impaired by Contagious Sleepiness
por: Tietäväinen, Aino, et al.
Publicado: (2018)

The use of an online Epworth Sleepiness Scale to assess excessive daytime sleepiness
por: Boyes, Jennifer, et al.
Publicado: (2016)

Nitric Oxide and Hydrogen Peroxide Production are Involved in Systemic Drought Tolerance Induced by 2R,3R-Butanediol in Arabidopsis thaliana
por: Cho, Song-Mi, et al.
Publicado: (2013)

Enhancement of 2,3-Butanediol Production by Klebsiella oxytoca PTCC 1402
por: Anvari, Maesomeh, et al.
Publicado: (2011)

Biodegradation-inspired bioproduction of methylacetoin and 2-methyl-2,3-butanediol
por: Jiang, Xinglin, et al.
Publicado: (2013)

Biotransformation of acetoin to 2,3-butanediol: Assessment of plant and microbial biocatalysts
por: Javidnia, Katayoun, et al.
Publicado: (2016)

Quorum and Light Signals Modulate Acetoin/Butanediol Catabolism in Acinetobacter spp.
por: Tuttobene, Marisel Romina, et al.
Publicado: (2019)

Unraveling 1,4-Butanediol Metabolism in Pseudomonas putida KT2440
por: Li, Wing-Jin, et al.
Publicado: (2020)

The current strategies and parameters for the enhanced microbial production of 2,3-butanediol
por: Hakizimana, Olivier, et al.
Publicado: (2019)

Leptin sensitizing effect of 1,3-butanediol and its potential mechanism
por: Isoda, Masayo, et al.
Publicado: (2021)

Cell-free synthetic biochemistry upgrading of ethanol to 1,3 butanediol
por: Liu, Hongjiang, et al.
Publicado: (2021)

Development of an industrial yeast strain for efficient production of 2,3-butanediol
por: Huo, Guangxin, et al.
Publicado: (2022)

Excessive daytime sleepiness and antipathogen drug consumption in the elderly: a test of the immune theory of sleep
por: Berticat, Claire, et al.
Publicado: (2016)

Craniofacial Characteristics Related to Daytime Sleepiness Screened by the Paediatric Daytime Sleepiness Scale
por: Gu, Min, et al.
Publicado: (2015)

Observation and Interview-based Diurnal Sleepiness Inventory for measurement of sleepiness in older adults
por: Pak, Victoria M, et al.
Publicado: (2017)

Excessive daytime sleepiness versus sleepiness at the wheel, the need to differentiate global from situational sleepiness to better predict sleep-related accidents
por: Philip, Pierre
Publicado: (2023)

High Production of 2,3-butanediol by a Mutant Strain of the Newly Isolated Klebsiella pneumoniae SRP2 with Increased Tolerance Towards Glycerol
por: Rahman, Md. Shafiqur, et al.
Publicado: (2017)

Tolerability and Safety of a Novel Ketogenic Ester, Bis-Hexanoyl (R)-1,3-Butanediol: A Randomized Controlled Trial in Healthy Adults
por: Chen, Oliver, et al.
Publicado: (2021)

Production of 2,3-butanediol in Saccharomyces cerevisiae by in silico aided metabolic engineering
por: Ng, Chiam Yu, et al.
Publicado: (2012)

Thermophilic fermentation of acetoin and 2,3-butanediol by a novel Geobacillus strain
por: Xiao, Zijun, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pnsg2eeqjnd2sgujvmpnc5ti2r