Application of an Integrative Drug Safety Model for Detection of Adverse Drug Events Associated With Inhibition of Glutathione Peroxidase 1 in Chronic Obstructive Pulmonary Disease

BACKGROUND: Chronic Obstructive Pulmonary Disease is characterised by declining lung function and a greater oxidative stress burden due to reduced activity of antioxidant enzymes such as Glutathione Peroxidase 1. OBJECTIVES: The extent to which drugs may contribute to this compromised activity is la...

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Detalles Bibliográficos
Autores principales: Janetzki, Jack L., Pratt, Nicole L., Ward, Michael B., Sykes, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338407/
https://www.ncbi.nlm.nih.gov/pubmed/37173537
http://dx.doi.org/10.1007/s11095-023-03516-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338407/
https://www.ncbi.nlm.nih.gov/pubmed/37173537
http://dx.doi.org/10.1007/s11095-023-03516-x

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