Synthesis and preclinical evaluation of a novel fluorine-18 labeled small-molecule PET radiotracer for imaging of CXCR3 receptor in mouse models of atherosclerosis

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BACKGROUND: CXCR3 is a chemokine receptor and is expressed in innate and adaptive immune cells. It promotes the recruitment of T-lymphocytes and other immune cells to the inflammatory site in response to the binding of cognate chemokines. Upregulation of CXCR3 and its chemokines has been found durin...

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Detalles Bibliográficos
Autores principales: Alluri, Santosh R., Higashi, Yusuke, Berendzen, Ashley, Grisanti, Laurel A., Watkinson, Lisa D., Singh, Kamlendra, Hoffman, Timothy J., Carmack, Terry, Devanny, Elizabeth A., Tanner, Miles, Kil, Kun-Eek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338423/
https://www.ncbi.nlm.nih.gov/pubmed/37438543
http://dx.doi.org/10.1186/s13550-023-01017-x
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