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Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy

Familial hypertrophic cardiomyopathy (FHC) patients are advised to avoid strenuous exercise due to increased risk of arrhythmias. Mice expressing the human FHC-causing mutation R403Q in the myosin heavy chain gene (MYH6) recapitulate the human phenotype, including cytoskeletal disarray and increased...

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Detalles Bibliográficos
Autores principales:	Cserne Szappanos, Henrietta, Viola, Helena M., Ito, Danica W., Lim, Seakcheng, Mangala, Melissa, Holliday, Mira, Barratt Ross, Samantha, Semsarian, Christopher, Hill, Adam, Dixon, Rose E., Hool, Livia C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338442/ https://www.ncbi.nlm.nih.gov/pubmed/37438479 http://dx.doi.org/10.1038/s41598-023-38296-2

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