Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile

Severe outbreaks and deaths have been linked to the emergence and global spread of fluoroquinolone-resistant Clostridioides difficile over the past two decades. At the same time, metronidazole, a nitro-containing antibiotic, has shown decreasing clinical efficacy in treating C. difficile infection (...

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Detalles Bibliográficos
Autores principales: Olaitan, Abiola O., Dureja, Chetna, Youngblom, Madison A., Topf, Madeline A., Shen, Wan-Jou, Gonzales-Luna, Anne J., Deshpande, Aditi, Hevener, Kirk E., Freeman, Jane, Wilcox, Mark H., Palmer, Kelli L., Garey, Kevin W., Pepperell, Caitlin S., Hurdle, Julian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338468/
https://www.ncbi.nlm.nih.gov/pubmed/37438331
http://dx.doi.org/10.1038/s41467-023-39429-x

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