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Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

The neuronal RNA-binding protein Ptbp2 regulates neuronal differentiation by modulating alternative splicing programs in the nucleus. Such programs contribute to axonogenesis by adjusting the levels of protein isoforms involved in axon growth and branching. While its functions in alternative splicin...

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Detalles Bibliográficos
Autores principales:	Salehi, Saeede, Zare, Abdolhossein, Prezza, Gianluca, Bader, Jakob, Schneider, Cornelius, Fischer, Utz, Meissner, Felix, Mann, Matthias, Briese, Michael, Sendtner, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338680/ https://www.ncbi.nlm.nih.gov/pubmed/37438340 http://dx.doi.org/10.1038/s41467-023-39787-6

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