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The MOM1 complex recruits the RdDM machinery via MORC6 to establish de novo DNA methylation

MORPHEUS’ MOLECULE1 (MOM1) is an Arabidopsis factor previously shown to mediate transcriptional silencing independent of major DNA methylation changes. Here we find that MOM1 localizes with sites of RNA-directed DNA methylation (RdDM). Tethering MOM1 with an artificial zinc finger to an unmethylated...

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Detalles Bibliográficos
Autores principales: Li, Zheng, Wang, Ming, Zhong, Zhenhui, Gallego-Bartolomé, Javier, Feng, Suhua, Jami-Alahmadi, Yasaman, Wang, Xinyi, Wohlschlegel, James, Bischof, Sylvain, Long, Jeff A., Jacobsen, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338684/
https://www.ncbi.nlm.nih.gov/pubmed/37438334
http://dx.doi.org/10.1038/s41467-023-39751-4