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Association between motoric cognitive risk syndrome and future falls among Chinese community‐dwelling elderly: A nationwide cohort study

BACKGROUND: Motoric Cognitive Risk syndrome (MCR), known as the predementia stage, is characterized by both subjective cognitive complaint (SCC) and slow gait. This study aimed to investigate the causal relationship between MCR, its components, and falls. METHODS: Participants aged ≥ 60 years were s...

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Autores principales: Lu, Wei‐wei, Liu, Bang‐zhong, Lv, Min‐zhi, Tu, Jin‐kang, Kang, Zi‐rui, Hu, Rui‐Ping, Zhu, Yu‐Lian, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338852/
https://www.ncbi.nlm.nih.gov/pubmed/37203236
http://dx.doi.org/10.1002/brb3.3044
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author Lu, Wei‐wei
Liu, Bang‐zhong
Lv, Min‐zhi
Tu, Jin‐kang
Kang, Zi‐rui
Hu, Rui‐Ping
Zhu, Yu‐Lian
Zhang, Jian
author_facet Lu, Wei‐wei
Liu, Bang‐zhong
Lv, Min‐zhi
Tu, Jin‐kang
Kang, Zi‐rui
Hu, Rui‐Ping
Zhu, Yu‐Lian
Zhang, Jian
author_sort Lu, Wei‐wei
collection PubMed
description BACKGROUND: Motoric Cognitive Risk syndrome (MCR), known as the predementia stage, is characterized by both subjective cognitive complaint (SCC) and slow gait. This study aimed to investigate the causal relationship between MCR, its components, and falls. METHODS: Participants aged ≥ 60 years were selected from China Health and Retirement Longitudinal Study. SCC was determined by participants' responses to the question “How would you rate your memory at present?” with “poor” being the indicative answer. Slow gait was defined as one standard deviation or more below age‐ and gender‐appropriate mean values of gait speed. MCR was identified when both SCC and slow gait were presented. Future falls were investigated by the question “have you fallen down during follow‐up until wave 4 in 2018?” Logistic regression analysis was performed to test the longitudinal association of MCR, its components and future falls during the following 3 years. RESULTS: Of 3748 samples in this study, the prevalence of MCR, SCC, and slow gait was 5.92%, 33.06%, and 15.21%, respectively. MCR increased the risk of falls during the following 3 years by 66.7% compared to non‐MCR after controlling for covariates. In the fully adjusted models, with the healthy group as reference, MCR (OR = 1.519, 95%CI = 1.086–2.126) and SCC (OR = 1.241, 95%CI = 1.018–1.513), but not slow gait, increased the risk of future falls. CONCLUSIONS: MCR independently predicts future falls risk in the following 3 years. Measuring MCR can be a pragmatic tool for early identification of falls risk.
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spelling pubmed-103388522023-07-14 Association between motoric cognitive risk syndrome and future falls among Chinese community‐dwelling elderly: A nationwide cohort study Lu, Wei‐wei Liu, Bang‐zhong Lv, Min‐zhi Tu, Jin‐kang Kang, Zi‐rui Hu, Rui‐Ping Zhu, Yu‐Lian Zhang, Jian Brain Behav Original Articles BACKGROUND: Motoric Cognitive Risk syndrome (MCR), known as the predementia stage, is characterized by both subjective cognitive complaint (SCC) and slow gait. This study aimed to investigate the causal relationship between MCR, its components, and falls. METHODS: Participants aged ≥ 60 years were selected from China Health and Retirement Longitudinal Study. SCC was determined by participants' responses to the question “How would you rate your memory at present?” with “poor” being the indicative answer. Slow gait was defined as one standard deviation or more below age‐ and gender‐appropriate mean values of gait speed. MCR was identified when both SCC and slow gait were presented. Future falls were investigated by the question “have you fallen down during follow‐up until wave 4 in 2018?” Logistic regression analysis was performed to test the longitudinal association of MCR, its components and future falls during the following 3 years. RESULTS: Of 3748 samples in this study, the prevalence of MCR, SCC, and slow gait was 5.92%, 33.06%, and 15.21%, respectively. MCR increased the risk of falls during the following 3 years by 66.7% compared to non‐MCR after controlling for covariates. In the fully adjusted models, with the healthy group as reference, MCR (OR = 1.519, 95%CI = 1.086–2.126) and SCC (OR = 1.241, 95%CI = 1.018–1.513), but not slow gait, increased the risk of future falls. CONCLUSIONS: MCR independently predicts future falls risk in the following 3 years. Measuring MCR can be a pragmatic tool for early identification of falls risk. John Wiley and Sons Inc. 2023-05-18 /pmc/articles/PMC10338852/ /pubmed/37203236 http://dx.doi.org/10.1002/brb3.3044 Text en © 2023 The Authors. Brain and Behavior published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Lu, Wei‐wei
Liu, Bang‐zhong
Lv, Min‐zhi
Tu, Jin‐kang
Kang, Zi‐rui
Hu, Rui‐Ping
Zhu, Yu‐Lian
Zhang, Jian
Association between motoric cognitive risk syndrome and future falls among Chinese community‐dwelling elderly: A nationwide cohort study
title Association between motoric cognitive risk syndrome and future falls among Chinese community‐dwelling elderly: A nationwide cohort study
title_full Association between motoric cognitive risk syndrome and future falls among Chinese community‐dwelling elderly: A nationwide cohort study
title_fullStr Association between motoric cognitive risk syndrome and future falls among Chinese community‐dwelling elderly: A nationwide cohort study
title_full_unstemmed Association between motoric cognitive risk syndrome and future falls among Chinese community‐dwelling elderly: A nationwide cohort study
title_short Association between motoric cognitive risk syndrome and future falls among Chinese community‐dwelling elderly: A nationwide cohort study
title_sort association between motoric cognitive risk syndrome and future falls among chinese community‐dwelling elderly: a nationwide cohort study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338852/
https://www.ncbi.nlm.nih.gov/pubmed/37203236
http://dx.doi.org/10.1002/brb3.3044
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