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The micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study
BACKGROUND: A low micronutrient intake has been reported to contribute to the double-burden of obesity, increasing the risk for chronic diseases such as cardiovascular disease, diabetes, cancer, and mental disorders. This case-control study compared micronutrient intake profiles in overweight/obese...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338876/ https://www.ncbi.nlm.nih.gov/pubmed/37457985 http://dx.doi.org/10.3389/fnut.2023.1148183 |
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author | Vahid, Farhad Rahmani, Wena Davoodi, Sayed Hossein Bohn, Torsten |
author_facet | Vahid, Farhad Rahmani, Wena Davoodi, Sayed Hossein Bohn, Torsten |
author_sort | Vahid, Farhad |
collection | PubMed |
description | BACKGROUND: A low micronutrient intake has been reported to contribute to the double-burden of obesity, increasing the risk for chronic diseases such as cardiovascular disease, diabetes, cancer, and mental disorders. This case-control study compared micronutrient intake profiles in overweight/obese vs. normal-weight individuals. We hypothesized that a low intake of certain micronutrients would increase the odds of being overweight/obese. METHODS: The case group (n = 812 adults) consisted of individuals with a BMI of ≥25 kg/m(2), and the control group (n = 793) had BMIs of 17.9–24.9 kg/m(2). A validated 124-item food frequency questionnaire was used to determine micronutrient-related dietary-quality, using the index of nutritional quality (INQ), calculated as the fraction of a micronutrient consumed vs. its dietary requirement. In addition, body surface area (BSA) was calculated according to the Mosteller formula. RESULTS: The control group had significantly higher INQ-scores of vitamin A, vitamin C, calcium, magnesium, and selenium compared to the case group. Furthermore, individuals with normal BSA (≤1.91 m(2) for men; ≤1.71 m(2) for women) had significantly higher INQ scores of vitamin C, calcium, magnesium, and zinc compared to participants with high BSA. In multivariable adjustment regression models, INQs of vitamin C (OR(BMI) = 0.79, 95%CI: 0.64–0.97; OR(BSA) = 0.81, 95%CI, 0.68–0.97) and magnesium (OR(BMI) = 0.69, 95%CI: 0.47–0.99; OR(BSA) = 0.71, 95%CI: 0.52–0.97) were significantly associated with the odds of obesity/overweight (in both BMI and BSA categories). CONCLUSION: The significant association between micronutrient levels of the diet, especially of vitamin C and magnesium, with both obesity criteria, emphasized the importance of certain micronutrients in the obesity/overweight causal network. |
format | Online Article Text |
id | pubmed-10338876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103388762023-07-14 The micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study Vahid, Farhad Rahmani, Wena Davoodi, Sayed Hossein Bohn, Torsten Front Nutr Nutrition BACKGROUND: A low micronutrient intake has been reported to contribute to the double-burden of obesity, increasing the risk for chronic diseases such as cardiovascular disease, diabetes, cancer, and mental disorders. This case-control study compared micronutrient intake profiles in overweight/obese vs. normal-weight individuals. We hypothesized that a low intake of certain micronutrients would increase the odds of being overweight/obese. METHODS: The case group (n = 812 adults) consisted of individuals with a BMI of ≥25 kg/m(2), and the control group (n = 793) had BMIs of 17.9–24.9 kg/m(2). A validated 124-item food frequency questionnaire was used to determine micronutrient-related dietary-quality, using the index of nutritional quality (INQ), calculated as the fraction of a micronutrient consumed vs. its dietary requirement. In addition, body surface area (BSA) was calculated according to the Mosteller formula. RESULTS: The control group had significantly higher INQ-scores of vitamin A, vitamin C, calcium, magnesium, and selenium compared to the case group. Furthermore, individuals with normal BSA (≤1.91 m(2) for men; ≤1.71 m(2) for women) had significantly higher INQ scores of vitamin C, calcium, magnesium, and zinc compared to participants with high BSA. In multivariable adjustment regression models, INQs of vitamin C (OR(BMI) = 0.79, 95%CI: 0.64–0.97; OR(BSA) = 0.81, 95%CI, 0.68–0.97) and magnesium (OR(BMI) = 0.69, 95%CI: 0.47–0.99; OR(BSA) = 0.71, 95%CI: 0.52–0.97) were significantly associated with the odds of obesity/overweight (in both BMI and BSA categories). CONCLUSION: The significant association between micronutrient levels of the diet, especially of vitamin C and magnesium, with both obesity criteria, emphasized the importance of certain micronutrients in the obesity/overweight causal network. Frontiers Media S.A. 2023-06-29 /pmc/articles/PMC10338876/ /pubmed/37457985 http://dx.doi.org/10.3389/fnut.2023.1148183 Text en Copyright © 2023 Vahid, Rahmani, Davoodi and Bohn. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Nutrition Vahid, Farhad Rahmani, Wena Davoodi, Sayed Hossein Bohn, Torsten The micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study |
title | The micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study |
title_full | The micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study |
title_fullStr | The micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study |
title_full_unstemmed | The micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study |
title_short | The micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study |
title_sort | micronutrient content of the diet is correlated with serum glucose biomarkers and lipid profile and is associated with the odds of being overweight/obese—a case-control study |
topic | Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338876/ https://www.ncbi.nlm.nih.gov/pubmed/37457985 http://dx.doi.org/10.3389/fnut.2023.1148183 |
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