Cargando…

The ATP sensitive potassium channel (K(ATP)) is a novel target for migraine drug development

Migraine is one of the leading causes of disability worldwide, affecting work and social life. It has been estimated that sales of migraine medicines will reach 12.9 billion USD in 2027. To reduce social impact, migraine treatments must improve, and the ATP-sensitive potassium (K(ATP)) channel is a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clement, Amalie, Christensen, Sarah Louise, Jansen-Olesen, Inger, Olesen, Jes, Guo, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338883/ https://www.ncbi.nlm.nih.gov/pubmed/37456521 http://dx.doi.org/10.3389/fnmol.2023.1182515

Ejemplares similares

ATP-Sensitive Potassium Channels in Migraine: Translational Findings and Therapeutic Potential
por: Clement, Amalie, et al.
Publicado: (2022)

Pharmacological Profiling of K(ATP) Channel Modulators: An Outlook for New Treatment Opportunities for Migraine
por: Dyhring, Tino, et al.
Publicado: (2023)

The K(ATP) channel in migraine pathophysiology: a novel therapeutic target for migraine
por: Al-Karagholi, Mohammad Al-Mahdi, et al.
Publicado: (2017)

The dynamic interplay of PIP(2) and ATP in the regulation of the K(ATP) channel
por: Pipatpolkai, Tanadet, et al.
Publicado: (2022)

ATP-sensitive potassium channel (K(ATP )channel) expression in the normal canine pancreas and in canine insulinomas
por: Donley, Vicky R, et al.
Publicado: (2005)

Increase of ATP-sensitive potassium (K(ATP)) channels in the heart of type-1 diabetic rats
por: Chen, Zhih-Cherng, et al.
Publicado: (2012)

Modulatory Effect of Medicinal Plants and Their Active Constituents on ATP-Sensitive Potassium Channels (K(ATP)) in Diabetes
por: Al Kury, Lina T.
Publicado: (2023)

Endothelial biology and ATP-sensitive potassium channels
por: Aziz, Qadeer, et al.
Publicado: (2018)

Identification of an ATP-sensitive potassium channel in mitochondria
por: Paggio, Angela, et al.
Publicado: (2019)

Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP
por: Trapp, Stefan, et al.
Publicado: (1998)

A unique inbred rat strain with sustained cephalic hypersensitivity as a model of chronic migraine-like pain
por: Munro, Gordon, et al.
Publicado: (2018)

Expression of ATP-sensitive potassium channels in human pregnant myometrium
por: Xu, Chen, et al.
Publicado: (2011)

Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels
por: Martin, Gregory M., et al.
Publicado: (2013)

Phosphoinositides Decrease Atp Sensitivity of the Cardiac Atp-Sensitive K(+) Channel: A Molecular Probe for the Mechanism of Atp-Sensitive Inhibition
por: Fan, Zheng, et al.
Publicado: (1999)

Ocular Hypotensive Properties and Biochemical Profile of QLS-101, a Novel ATP-Sensitive Potassium (K(ATP)) Channel Opening Prodrug
por: Pervan-Steel, Cynthia L., et al.
Publicado: (2022)

Activation mechanism of ATP-sensitive K(+) channels explored with real-time nucleotide binding
por: Puljung, Michael, et al.
Publicado: (2019)

Nucleotide inhibition of the pancreatic ATP-sensitive K(+) channel explored with patch-clamp fluorometry
por: Usher, Samuel G, et al.
Publicado: (2020)

Regulation of myometrial contraction by ATP-sensitive potassium (K(ATP)) channel via activation of SUR2B and Kir 6.2 in mouse
por: HONG, Seung Hwa, et al.
Publicado: (2016)

ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway
por: Roy Chowdhury, Uttio, et al.
Publicado: (2017)

Evidence for the Participation of ATP-sensitive Potassium Channels in the Antinociceptive Effect of Curcumin
por: De Paz-Campos, Marco Antonio, et al.
Publicado: (2012)

Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia
por: Turzo, Maurizio, et al.
Publicado: (2018)

How ATP Inhibits the Open K(ATP) Channel
por: Craig, Tim J., et al.
Publicado: (2008)

BAD and K(ATP) channels regulate neuron excitability and epileptiform activity
por: Martínez-François, Juan Ramón, et al.
Publicado: (2018)

Exploitation of ATP-sensitive potassium ion (K(ATP)) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling
por: Scarth, James A., et al.
Publicado: (2023)

ATP-Sensitive Potassium Channel-Deficient Mice Show Hyperphagia but Are Resistant to Obesity
por: Park, Yeul Bum, et al.
Publicado: (2011)

Functional protection against cardiac diseases depends on ATP‐sensitive potassium channels
por: Ye, Peng, et al.
Publicado: (2018)

Endothelial ATP-Sensitive Potassium Channel Protects Against the Development of Hypertension and Atherosclerosis
por: Li, Yiwen, et al.
Publicado: (2020)

The Potential Role of Activating the ATP-Sensitive Potassium Channel in the Treatment of Hyperphagic Obesity
por: Cowen, Neil, et al.
Publicado: (2020)

Hypoxia Promotes Atrial Tachyarrhythmias via Opening of ATP-Sensitive Potassium Channels
por: Specterman, Mark J., et al.
Publicado: (2023)

Trapping endoplasmic reticulum with amphiphilic AIE-active sensor via specific interaction of ATP-sensitive potassium (K(ATP))
por: Zhu, Zhirong, et al.
Publicado: (2020)

Mice expressing a human K(ATP) channel mutation have altered channel ATP sensitivity but no cardiac abnormalities
por: Clark, R., et al.
Publicado: (2012)

Single-Channel Properties of the ROMK-Pore-Forming Subunit of the Mitochondrial ATP-Sensitive Potassium Channel
por: Laskowski, Michał, et al.
Publicado: (2019)

Mechanism of ATP-sensitive K Channel Inhibition by Sulfhydryl Modification
por: Trapp, Stefan, et al.
Publicado: (1998)

Surface charge and properties of cardiac ATP-sensitive K+ channels
Publicado: (1994)

Localization of ATP-sensitive K(+) channel subunits in rat liver
por: Zhou, Ming, et al.
Publicado: (2019)

Targeting ATP-Sensitive K(+) Channels to Treat Pulmonary Hypertension
por: Breen, Ellen, et al.
Publicado: (2022)

Histamine and migraine revisited: mechanisms and possible drug targets
por: Worm, Jacob, et al.
Publicado: (2019)

Mechanism of pharmacochaperoning in a mammalian K(ATP) channel revealed by cryo-EM
por: Martin, Gregory M, et al.
Publicado: (2019)

Role of Hsp90 in Biogenesis of the β-Cell ATP-sensitive Potassium Channel Complex
por: Yan, Fei-Fei, et al.
Publicado: (2010)

Mitochondria from rat uterine smooth muscle possess ATP-sensitive potassium channel
por: Vadzyuk, Olga B., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_i9g3f1ulb8uiruq4mkascrsi6f