CD26(low)PD-1(+) CD8 T cells are terminally exhausted and associated with leukemia progression in acute myeloid leukemia

Acute myeloid leukemia (AML) is a devastating blood cancer with poor prognosis. Novel effective treatment is an urgent unmet need. Immunotherapy targeting T cell exhaustion by blocking inhibitory pathways, such as PD-1, is promising in cancer treatment. However, results from clinical studies applyin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Huarong, Jia, Bei, Annageldiyev, Charyguly, Minagawa, Kentaro, Zhao, Chenchen, Mineishi, Shin, Ehmann, W Christopher, Naik, Seema G., Cioccio, Joseph, Wirk, Baldeep, Songdej, Natthapol, Rakszawski, Kevin L., Nickolich, Myles S., Shen, Jianzhen, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338956/
https://www.ncbi.nlm.nih.gov/pubmed/37457737
http://dx.doi.org/10.3389/fimmu.2023.1169144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338956/
https://www.ncbi.nlm.nih.gov/pubmed/37457737
http://dx.doi.org/10.3389/fimmu.2023.1169144

Ejemplares similares