Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2

Extracellular adherence protein domain (EAP) proteins are high-affinity, selective inhibitors of neutrophil serine proteases (NSP), including cathepsin-G (CG) and neutrophil elastase (NE). Most Staphylococcus aureus isolates encode for two EAPs, EapH1 and EapH2, that contain a single functional doma...

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Detalles Bibliográficos
Autores principales: Mishra, Nitin, Herdendorf, Timothy J., Prakash, Om, Geisbrecht, Brian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339191/
https://www.ncbi.nlm.nih.gov/pubmed/37269950
http://dx.doi.org/10.1016/j.jbc.2023.104878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339191/
https://www.ncbi.nlm.nih.gov/pubmed/37269950
http://dx.doi.org/10.1016/j.jbc.2023.104878

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