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Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2
Extracellular adherence protein domain (EAP) proteins are high-affinity, selective inhibitors of neutrophil serine proteases (NSP), including cathepsin-G (CG) and neutrophil elastase (NE). Most Staphylococcus aureus isolates encode for two EAPs, EapH1 and EapH2, that contain a single functional doma...
Autores principales: | Mishra, Nitin, Herdendorf, Timothy J., Prakash, Om, Geisbrecht, Brian V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339191/ https://www.ncbi.nlm.nih.gov/pubmed/37269950 http://dx.doi.org/10.1016/j.jbc.2023.104878 |
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