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IDH1 K224 acetylation promotes colorectal cancer via miR-9-5p/NHE1 axis-mediated regulation of acidic microenvironment

The acidic microenvironment is considered an important factor in colorectal cancer (CRC) that contributes to malignant transformation. However, the underlying mechanism remains unclear. In a previous study, we confirmed that IDH1 K224 deacetylation promotes enzymatic activity and the production of α...

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Detalles Bibliográficos
Autores principales:	Wang, Bo, Zhao, Long, Yang, Changjiang, Lin, Yilin, Wang, Shan, Ye, Yingjiang, Luo, Jianyuan, Shen, Zhanlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339209/ https://www.ncbi.nlm.nih.gov/pubmed/37456829 http://dx.doi.org/10.1016/j.isci.2023.107206

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