COVID-19 severity: does the genetic landscape of rare variants matter?

Rare variants affecting host defense against pathogens may be involved in COVID-19 severity, but most rare variants are not expected to have a major impact on the course of COVID-19. We hypothesized that the accumulation of weak effects of many rare functional variants throughout the exome may contr...

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Detalles Bibliográficos
Autores principales: Khadzhieva, Maryam B., Gracheva, Alesya S., Belopolskaya, Olesya B., Kolobkov, Dmitry S., Kashatnikova, Darya A., Redkin, Ivan V., Kuzovlev, Artem N., Grechko, Andrey V., Salnikova, Lyubov E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339319/
https://www.ncbi.nlm.nih.gov/pubmed/37456666
http://dx.doi.org/10.3389/fgene.2023.1152768

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