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Elevated CHCHD4 orchestrates mitochondrial oxidative phosphorylation to disturb hypoxic pulmonary hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is a highly prevalent cardiopulmonary disorder characterized by vascular remodeling and increased resistance in pulmonary artery. Mitochondrial coiled–coil–helix–coiled–coil–helix domain (CHCHD)-containing proteins have various important pathophysiol...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Zeng, Zhenyu, Zeng, Zhaoxiang, Chu, Guojun, Shan, Xinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339524/ https://www.ncbi.nlm.nih.gov/pubmed/37438854 http://dx.doi.org/10.1186/s12967-023-04268-3

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