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Effect of aging on the formation and growth of colonic epithelial organoids by changes in cell cycle arrest through TGF-β-Smad3 signaling

BACKGROUND: This study aimed to investigate how aging alters the homeostasis of the colonic intestinal epithelium and regeneration after tissue injury using organoid models and to identify its underlying molecular mechanism. METHODS: To investigate aging-related changes in the colonic intestinal epi...

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Detalles Bibliográficos
Autores principales:	Jo, Min Kyoung, Moon, Chang Mo, Jeon, Hyeon-Jeong, Han, Yerim, Lee, Eun Sook, Kwon, Ji-Hee, Yang, Kyung-Min, Ahn, Young-Ho, Kim, Seong-Eun, Jung, Sung-Ae, Kim, Tae Il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339613/ https://www.ncbi.nlm.nih.gov/pubmed/37438837 http://dx.doi.org/10.1186/s41232-023-00282-6

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