Assessing the performance of European-derived cardiometabolic polygenic risk scores in South-Asians and their interplay with family history

BACKGROUND & AIMS: We aimed to assess the performance of European-derived polygenic risk scores (PRSs) for common metabolic diseases such as coronary artery disease (CAD), obesity, and type 2 diabetes (T2D) in the South Asian (SAS) individuals in the UK Biobank. Additionally, we studied the inte...

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Detalles Bibliográficos
Autores principales: Hassanin, Emadeldin, Maj, Carlo, Klinkhammer, Hannah, Krawitz, Peter, May, Patrick, Bobbili, Dheeraj Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339617/
https://www.ncbi.nlm.nih.gov/pubmed/37438803
http://dx.doi.org/10.1186/s12920-023-01598-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339617/
https://www.ncbi.nlm.nih.gov/pubmed/37438803
http://dx.doi.org/10.1186/s12920-023-01598-5

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