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Assessing the performance of European-derived cardiometabolic polygenic risk scores in South-Asians and their interplay with family history

BACKGROUND & AIMS: We aimed to assess the performance of European-derived polygenic risk scores (PRSs) for common metabolic diseases such as coronary artery disease (CAD), obesity, and type 2 diabetes (T2D) in the South Asian (SAS) individuals in the UK Biobank. Additionally, we studied the inte...

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Detalles Bibliográficos
Autores principales:	Hassanin, Emadeldin, Maj, Carlo, Klinkhammer, Hannah, Krawitz, Peter, May, Patrick, Bobbili, Dheeraj Reddy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339617/ https://www.ncbi.nlm.nih.gov/pubmed/37438803 http://dx.doi.org/10.1186/s12920-023-01598-5

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