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Safety analysis of new medications in clinical trials: a simulation study to assess the differences between cause-specific and subdistribution frameworks in the presence of competing events

Safety is an essential part of the evaluation of new medications and competing risks that occur in most clinical trials are a well identified challenge in the analysis of adverse events. Two statistical frameworks exist to consider competing risks: the cause-specific and the subdistribution framewor...

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Detalles Bibliográficos
Autores principales:	Genet, Astrid, Bogner, Kathrin, Goertz, Ralf, Böhme, Sarah, Leverkus, Friedhelm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339642/ https://www.ncbi.nlm.nih.gov/pubmed/37442979 http://dx.doi.org/10.1186/s12874-023-01985-7

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