Cargando…

Total Flavonoids from Rhizoma Drynariae (Gusuibu) Alleviates Diabetic Osteoporosis by Activating BMP2/Smad Signaling Pathway

INTRODUCTION: Diabetic osteoporosis (DOP) is a widespread public health problem. The flavonoids of Rhizoma Drynariae (RDF) have a clear preventive and therapeutic effect on osteoporosis (OP), but it is not yet clear whether RDF has an anti-DOP and whether its mechanism is related to the activation o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Xin Hua, Zhou, Guo Er, Lin, Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2023
Materias:	Chemistry, Combinatorial Chemistry and High Throughput Screening, Biochemical Research Methods, Chemistry, Applied Chemistry, Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339686/ https://www.ncbi.nlm.nih.gov/pubmed/36825725 http://dx.doi.org/10.2174/1386207326666230223165730

Ejemplares similares

Network Pharmacology-based Investigation of the Underlying Mechanism of Panax notoginseng Treatment of Diabetic Retinopathy
por: Piao, Chunli, et al.
Publicado: (2020)

Pitongshu Alleviates the Adverse Symptoms in Rats with Functional Dyspepsia Through Regulating Visceral Hypersensitivity Caused by 5-HT Overexpression
por: Chen, Su-Hong, et al.
Publicado: (2023)

Deep Learning for Predicting Distant Metastasis in Patients with Nasopharyngeal Carcinoma Based on Pre-Radiotherapy Magnetic Resonance Imaging
por: Hua, Hong-Li, et al.
Publicado: (2023)

HDL-Chitosan Nanoparticles for siRNA Delivery as an SR-B1 Receptor Targeted System
por: Masimov, Rasim, et al.
Publicado: (2023)

LincRNA-p21 Promotes Cellular Senescence by Down-regulating the Wnt/β-catenin Pathway in MPP(+)-treated SH-SY5Y Cells
por: Zhu, Jianyu, et al.
Publicado: (2023)

Identification of Chemokines-Related miRNAs as Potential Biomarkers in Psoriasis Based on Integrated Bioinformatics Analysis
por: Zhuang, Haojun, et al.
Publicado: (2023)

Gastric Cancer Growth Modulated by circSNTB2/miR-6938-5p/G0S2 and PDCD4
por: Rong, Baohai, et al.
Publicado: (2023)

Bridging Integrator 3 (BIN3) Downregulation Predicts a Poor Prognosis in Patients with Esophagus Carcinoma: A Study based on TCGA Data
por: Li, Daohang, et al.
Publicado: (2023)

Expression and Predictive Significance of FHL1 and SLIT3 in Surgically Resected Lung Adenocarcinoma
por: Song, Jinjing, et al.
Publicado: (2023)

Network Pharmacology Study on the Mechanism of Gastrodin Reversing Depressive Symptoms in Traumatically Stressed Rats
por: Zhao, Ruodan, et al.
Publicado: (2023)

Analysis of Pharmacological Activities and Mechanisms of Essential Oil in Leaves of C. grandis ‘Tomentosa’ by GC-MS/MS and Network Pharmacology
por: You, Jie-Shu, et al.
Publicado: (2023)

Dendrobium officinalis Six Nostrum Promotes Intestinal Urate Underexcretion via Regulations of Urate Transporter Proteins in Hyperuricemic Rats
por: Ge, Hongzhang, et al.
Publicado: (2023)

Penehyclidine Hydrochloride Protects Rat Cardiomyocytes from Ischemia-Reperfusion Injury by Platelet-derived Growth Factor-B
por: Lu, Yan, et al.
Publicado: (2023)

Exploring the Target and Mechanism of Radix Paeoniae Alba on Sjogren’s Syndrome
por: Wu, Fangping, et al.
Publicado: (2023)

Impact of Previous Pulmonary Tuberculosis on Chronic Obstructive Pulmonary Disease: Baseline Results from a Prospective Cohort Study
por: Wang, Yide, et al.
Publicado: (2023)

TIGIT as a Novel Prognostic Marker for Immune Infiltration in Invasive Breast Cancer
por: Guo, Chenming, et al.
Publicado: (2023)

Identification of Key Diagnostic Markers and Immune Infiltration in Osteoarthritis
por: Yan, Mingyue, et al.
Publicado: (2023)

Identification and Verification of Key MiRNAs Associated with Intervertebral Disc Degeneration
por: Liu, Jianwei, et al.
Publicado: (2023)

An Investigation of the Mechanism of Rapid Relief of Ulcerative Colitis Induced by Five-flavor Sophora Flavescens Enteric-coated Capsules Based on Network Pharmacology
por: Gu, Sizhen, et al.
Publicado: (2020)

Total flavonoids from Rhizoma Drynariae (Gusuibu) for treating osteoporotic fractures: implication in clinical practice
por: Zhang, Yili, et al.
Publicado: (2017)

Molecular Mechanisms of Notopterygii rhizoma Et Radix for Treating Arrhythmia Based on Network Pharmacology
por: Wei, Penglu, et al.
Publicado: (2023)

Exploration of the Mechanism of Tripterygium Wilfordii in the Treatment of Myocardial Fibrosis Based on Network Pharmacology and Molecular Docking
por: Ming, Yang, et al.
Publicado: (2023)

Exploring the Molecular Mechanism of HongTeng Decoction against Inflammation based on Network Analysis and Experiments Validation
por: Yang, Yuanyuan, et al.
Publicado: (2023)

Molecular Mechanism of Caulis Spatholobi in the Treatment of Chronic Myeloid Leukemia based on Network Pharmacology and Experimental Verification
por: Wu, Yanchun, et al.
Publicado: (2023)

Network Pharmacology and Intestinal Microbiota Analysis Revealing the Mechanism of Punicalagin Improving Bacterial Enteritis
por: Huang, Shuyun, et al.
Publicado: (2023)

Potential Mechanisms Underlying the Therapeutic Roles of Gancao fuzi Decoction in Cold-dampness Obstruction Syndrome-type Knee Osteoarthritis
por: Zhao, Jinlong, et al.
Publicado: (2023)

Comprehensive Analysis of Cuproptosis Genes and Identification of Cuproptosis Subtypes in Breast Cancer
por: Li, Jialin, et al.
Publicado: (2023)

A Novel Tumor Mutation Burden Related lncRNA Signature Identified Prognosis and Tumor Immune Microenvironment Features in Clear Cell Renal Cell Carcinoma
por: Lin, Lin, et al.
Publicado: (2023)

Study on the identification of Pinelliae rhizoma and Pinelliae pedatisectae rhizoma based on the characteristic component triglochinic acid
por: Jing, Yong, et al.
Publicado: (2019)

The antimicrobial peptide KR-12 promotes the osteogenic differentiation of human bone marrow stem cells by stimulating BMP/SMAD signaling
por: Li, Hui, et al.
Publicado: (2018)

Effect of Total Flavonoids of Rhizoma drynariae on Tibial Dyschondroplasia by Regulating BMP-2 and Runx2 Expression in Chickens
por: Yao, Wangyuan, et al.
Publicado: (2018)

Total flavonoids of Rhizoma Drynariae combined with calcium attenuate osteoporosis by reducing reactive oxygen species generation
por: Mu, Panyun, et al.
Publicado: (2021)

SKLB023 as an iNOS inhibitor alleviated liver fibrosis by inhibiting the TGF-beta/Smad signaling pathway
por: Zhang, Jinhang, et al.
Publicado: (2018)

Allele-specific assembly of a eukaryotic genome corrects apparent frameshifts and reveals a lack of nonsense-mediated mRNA decay
por: Cosentino, Raúl O, et al.
Publicado: (2021)

Ideafix: a decision tree-based method for the refinement of variants in FFPE DNA sequencing data
por: Tellaetxe-Abete, Maitena, et al.
Publicado: (2021)

High-scale random access on DNA storage systems
por: El-Shaikh, Alex, et al.
Publicado: (2022)

Fast and memory-efficient mapping of short bisulfite sequencing reads using a two-letter alphabet
por: de Sena Brandine, Guilherme, et al.
Publicado: (2021)

iLoci: robust evaluation of genome content and organization for provisional and mature genome assemblies
por: Standage, Daniel S, et al.
Publicado: (2022)

Optocoder: computational decoding of spatially indexed bead arrays
por: Senel, Enes, et al.
Publicado: (2022)

Systematic evaluation of parameters in RNA bisulfite sequencing data generation and analysis
por: Johnson, Zachary, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a03inos569glgma5vr4f3799j9