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Quantitative structure–activity relationship study of amide derivatives as xanthine oxidase inhibitors using machine learning
The target of the study is to predict the inhibitory effect of amide derivatives on xanthine oxidase (XO) by building several models, which are based on the theory of the quantitative structure–activity relationship (QSAR). The heuristic method (HM) was used to linearly select descriptors and build...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339742/ https://www.ncbi.nlm.nih.gov/pubmed/37456753 http://dx.doi.org/10.3389/fphar.2023.1227536 |