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Direct In Vivo Activation of T Cells with Nanosized Immunofilaments Inhibits Tumor Growth and Metastasis
[Image: see text] Adoptive T cell therapy has successfully been implemented for the treatment of cancer. Nevertheless, ex vivo expansion of T cells by artificial antigen-presenting cells (aAPCs) remains cumbersome and can compromise T cell functionality, thereby limiting their therapeutic potential....
Autores principales: | Weiss, Lea, Weiden, Jorieke, Dölen, Yusuf, Grad, Emilia M., van Dinther, Eric A. W., Schluck, Marjolein, Eggermont, Loek J., van Mierlo, Guido, Gileadi, Uzi, Bartoló-Ibars, Ariadna, Raavé, René, Gorris, Mark A. J., Maassen, Lisa, Verrijp, Kiek, Valente, Michael, Deplancke, Bart, Verdoes, Martijn, Benitez-Ribas, Daniel, Heskamp, Sandra, van Spriel, Annemiek B., Figdor, Carl G., Hammink, Roel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339791/ https://www.ncbi.nlm.nih.gov/pubmed/37338806 http://dx.doi.org/10.1021/acsnano.2c11884 |
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