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Fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: A case report

Aortic aneurysm is a potentially life‐threatening condition with higher incidence in patients with systemic lupus erythematosus(SLE). Patients usually present with nonspecific symptoms and diagnosis is typically made incidentally through imaging studies. Management strategies include medical therapy...

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Autores principales: Shahi, Tejash, Ghimire, Prinska, Khanal, Ujjwal Prakash, Dhakal, Tulsi Ram, Jha, Saket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340078/
https://www.ncbi.nlm.nih.gov/pubmed/37457996
http://dx.doi.org/10.1002/ccr3.7696
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author Shahi, Tejash
Ghimire, Prinska
Khanal, Ujjwal Prakash
Dhakal, Tulsi Ram
Jha, Saket
author_facet Shahi, Tejash
Ghimire, Prinska
Khanal, Ujjwal Prakash
Dhakal, Tulsi Ram
Jha, Saket
author_sort Shahi, Tejash
collection PubMed
description Aortic aneurysm is a potentially life‐threatening condition with higher incidence in patients with systemic lupus erythematosus(SLE). Patients usually present with nonspecific symptoms and diagnosis is typically made incidentally through imaging studies. Management strategies include medical therapy to control inflammation and hypertension, surgical intervention for large or symptomatic aneursyms, and close monitoring for early detection of complications. We present a case of a 49‐year female with multiple joint pain and other nonspecific symptoms for 7 years. Anti‐ds DNA and ANA titre were significantly high and CT angiogram showed ascending aortic aneurysm measuring 5.5 cm. Conservative management was started with steroids, hydroxychloroquine, and antihypertensives, while awaiting surgery. However she suddenly collapsed, probably due to aneurysm rupture and could not be revived. Our case report therefore emphasizes the importance of close surveillance and timely intervention to minimize the morbidity and mortality in these patients.
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spelling pubmed-103400782023-07-14 Fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: A case report Shahi, Tejash Ghimire, Prinska Khanal, Ujjwal Prakash Dhakal, Tulsi Ram Jha, Saket Clin Case Rep Case Report Aortic aneurysm is a potentially life‐threatening condition with higher incidence in patients with systemic lupus erythematosus(SLE). Patients usually present with nonspecific symptoms and diagnosis is typically made incidentally through imaging studies. Management strategies include medical therapy to control inflammation and hypertension, surgical intervention for large or symptomatic aneursyms, and close monitoring for early detection of complications. We present a case of a 49‐year female with multiple joint pain and other nonspecific symptoms for 7 years. Anti‐ds DNA and ANA titre were significantly high and CT angiogram showed ascending aortic aneurysm measuring 5.5 cm. Conservative management was started with steroids, hydroxychloroquine, and antihypertensives, while awaiting surgery. However she suddenly collapsed, probably due to aneurysm rupture and could not be revived. Our case report therefore emphasizes the importance of close surveillance and timely intervention to minimize the morbidity and mortality in these patients. John Wiley and Sons Inc. 2023-07-13 /pmc/articles/PMC10340078/ /pubmed/37457996 http://dx.doi.org/10.1002/ccr3.7696 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shahi, Tejash
Ghimire, Prinska
Khanal, Ujjwal Prakash
Dhakal, Tulsi Ram
Jha, Saket
Fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: A case report
title Fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: A case report
title_full Fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: A case report
title_fullStr Fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: A case report
title_full_unstemmed Fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: A case report
title_short Fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: A case report
title_sort fatal ascending aortic aneurysm in a patient with systemic lupus erythematosus: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340078/
https://www.ncbi.nlm.nih.gov/pubmed/37457996
http://dx.doi.org/10.1002/ccr3.7696
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