Cargando…

Melanoma Cells Inhibit iNKT Cell Functions via PGE2 and IDO1

SIMPLE SUMMARY: The unique properties of invariant natural killer T (iNKT) cells make them an attractive candidate for cancer-adoptive immunotherapy. However, despite their potential, clinical studies have not consistently shown successful outcomes. This lack of efficacy is likely attributed to the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Torre, Enza, Pinton, Giulia, Lombardi, Grazia, Fallarini, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340314/ https://www.ncbi.nlm.nih.gov/pubmed/37444608 http://dx.doi.org/10.3390/cancers15133498

Ejemplares similares

NKT10 cells: a novel iNKT cell subset
por: Wingender, Gerhard, et al.
Publicado: (2015)

iNKT and MAIT Cell Alterations in Diabetes
por: Magalhaes, Isabelle, et al.
Publicado: (2015)

The Role of Autophagy in iNKT Cell Development
por: Yang, Guan, et al.
Publicado: (2018)

Recent advances in iNKT cell development
por: Hogquist, Kristin, et al.
Publicado: (2020)

Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy
por: Aoki, Takahiro, et al.
Publicado: (2023)

Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model
por: Lee, Sung Won, et al.
Publicado: (2018)

The iNKT Cell–Macrophage Axis in Homeostasis and Disease
por: Cruz, Mariana S., et al.
Publicado: (2022)

β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation
por: Berga-Bolaños, Rosa, et al.
Publicado: (2015)

The Pathophysiological Relevance of the iNKT Cell/Mononuclear Phagocyte Crosstalk in Tissues
por: Cortesi, Filippo, et al.
Publicado: (2018)

NNKTT120, an anti-iNKT cell monoclonal antibody, produces rapid and sustained iNKT cell depletion in adults with sickle cell disease
por: Field, Joshua J., et al.
Publicado: (2017)

CD8(+) T-cell immunity orchestrated by iNKT cells
por: Qin, Yingyu, et al.
Publicado: (2023)

The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function
por: Locci, Michela, et al.
Publicado: (2009)

Primary Mouse Invariant Natural Killer T (iNKT) Cell Purification and Transduction
por: Delfanti, Gloria, et al.
Publicado: (2023)

The Ras/MAPK Pathway Is Required for Generation of iNKT Cells
por: Hu, Taishan, et al.
Publicado: (2011)

The transcriptional repressor NKAP is required for the development of iNKT cells
por: Thapa, Puspa, et al.
Publicado: (2013)

Histone deacetylase 3 is required for iNKT cell development
por: Thapa, Puspa, et al.
Publicado: (2017)

Enhancing Neuroblastoma Immunotherapies by Engaging iNKT and NK Cells
por: McNerney, Kevin O., et al.
Publicado: (2020)

Alterations of the iNKT cell compartment in brain-injured patients
por: Patinec, Allan, et al.
Publicado: (2019)

The impact of stress on the transcriptomic signature of iNKT1 cells
por: Papadogianni, Georgia, et al.
Publicado: (2021)

Human iNKT Cells Modulate Macrophage Survival and Phenotype
por: Loureiro, J. Pedro, et al.
Publicado: (2022)

New insights into iNKT cells and their roles in liver diseases
por: Gu, Xinyu, et al.
Publicado: (2022)

Adoptive Immunotherapy With Engineered iNKT Cells to Target Cancer Cells and the Suppressive Microenvironment
por: Delfanti, Gloria, et al.
Publicado: (2022)

A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease
por: Ren, Yue, et al.
Publicado: (2017)

Thymic stromal lymphopoietin production in DN32.D3 invariant natural killer T (iNKT) cell line and primary mouse liver iNKT cells
por: Choi, Jun-Pyo, et al.
Publicado: (2021)

Single-cell analysis reveals differences among iNKT cells colonizing peripheral organs and identifies Klf2 as a key gene for iNKT emigration
por: Wang, Jie, et al.
Publicado: (2022)

Tim‐3 blockade promotes iNKT cell function to inhibit HBV replication
por: Xu, Yong, et al.
Publicado: (2018)

miR-150 regulates the development of NK and iNKT cells
por: Bezman, Natalie A., et al.
Publicado: (2011)

iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis
por: Rothchild, Alissa C., et al.
Publicado: (2014)

An In Silico Approach for Modelling T-Helper Polarizing iNKT Cell Agonists
por: De Spiegeleer, Anton, et al.
Publicado: (2014)

Exploring the Therapeutic Potentials of iNKT Cells for Anti-HBV Treatment
por: Lawrenczyk, Agnieszka, et al.
Publicado: (2014)

iNKT Cells and Their Potential Lipid Ligands during Viral Infection
por: Opasawatchai, Anunya, et al.
Publicado: (2015)

Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors
por: Serafini, Marta, et al.
Publicado: (2019)

iNKT Cells Control Mouse Spontaneous Carcinoma Independently of Tumor-Specific Cytotoxic T Cells
por: Bellone, Matteo, et al.
Publicado: (2010)

iNKT cell development is orchestrated by different branches of TGF-β signaling
por: Doisne, Jean-Marc, et al.
Publicado: (2009)

BATF regulates the development and function of IL-17 producing iNKT cells
por: Jordan-Williams, Kimberly L, et al.
Publicado: (2013)

Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells
por: Cohen, Nadia R., et al.
Publicado: (2012)

Diacylglycerol Kinase Zeta Positively Controls the Development of iNKT-17 Cells
por: Wu, Jinhong, et al.
Publicado: (2013)

Humanizing mice for the identification of novel anticancer lipids targeting iNKT cells
por: Wen, Xiangshu, et al.
Publicado: (2013)

Oxidative stress-mediated iNKT-cell activation is involved in COPD pathogenesis
por: Pichavant, M, et al.
Publicado: (2014)

Regulated Expression of miR-155 is Required for iNKT Cell Development
por: Burocchi, Alessia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ovvsgrj9isu3qs2he3jescpgbc