Methylthiosulfonate-Based Cysteine Modifiers as Alternative Inhibitors of Mercurial-Sensitive Aquaporins

(1) Background: Several members of the ubiquitous aquaporin family, AQP, of water and neutral solute channels carry a cysteine residue in the selectivity filter region. Traditionally, toxic mercury-containing compounds are used to bind to the cysteine as covalent AQP inhibitors for physiological stu...

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Detalles Bibliográficos
Autores principales: Jeuken, Katrin, Jaeger, Emmi, Matthews, Emily, Beitz, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340331/
https://www.ncbi.nlm.nih.gov/pubmed/37443776
http://dx.doi.org/10.3390/cells12131742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340331/
https://www.ncbi.nlm.nih.gov/pubmed/37443776
http://dx.doi.org/10.3390/cells12131742

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