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Beyond the Complement Cascade: Insights into Systemic Immunosenescence and Inflammaging in Age-Related Macular Degeneration and Current Barriers to Treatment

Landmark genetic studies have revealed the effect of complement biology and its regulation on the pathogenesis of age-related macular degeneration (AMD). Limited phase 3 clinical trial data showing a benefit of complement inhibition in AMD raises the prospect of more complex mediators at play. Subst...

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Detalles Bibliográficos
Autores principales:	Khan, Adnan H., Chowers, Itay, Lotery, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340338/ https://www.ncbi.nlm.nih.gov/pubmed/37443742 http://dx.doi.org/10.3390/cells12131708

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