Microwave-accelerated cross-dehydrogenative-coupling (CDC) of N-(quinolin-8-yl)amides with acetone/acetonitrile under metal-free conditions

A highly selective remote C(sp(3))–H acetonation of N-(quinolin-8-yl)amide scaffolds at the C5-position under microwave irradiation has been developed. In the absence of a transition-metal-catalyst, benzoyl peroxide (BPO)-promoted cross-dehydrogenation coupling (CDC) of N-(quinolin-8-yl)amides with...

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Detalles Bibliográficos
Autores principales: Zhou, Chao, Liu, Yunwei, Luo, Qi, Zhang, Yicheng, Zhou, Jingwen, Zhang, Haoyu, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340454/
https://www.ncbi.nlm.nih.gov/pubmed/37456538
http://dx.doi.org/10.1039/d3ra03651k

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